Translation of liver stage activity of m5717, a plasmodium elongation factor 2 inhibitor: from bench to bedside

HIGHLIGHTS

  • who: Akash Khandelwal from the The healthcare business of Merck KGaA, Darmstadt, Germany have published the research work: Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside, in the Journal: (JOURNAL)
  • what: This approach has the potential to accelerate the search for new anti-malarials to reduce the number of healthy volunteers needed in a clinical study and decrease and refine the animal use in the preclinical phase. The model was derived from results obtained from the completed Phase 1 clinical trial .
  • how: In both . . .

     

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