Translational development of abcb5

HIGHLIGHTS

  • who: Andreas Kerstan from the TICEBA GmbH, Im Neuenheimer Feld, Heidelberg, Germany have published the research work: Translational development of ABCB5, in the Journal: (JOURNAL) of 30/08/2017
  • what: The authors demonstrate that skin-derived A u00ad BCB5+ MSCs adaptively activate the proangiogenic HIF-1 pathway in response to hypoxic conditions. This studies demonstrate the in_vitro and in_vivo angiogenic potential of u00adABCB5+ MSCs based on both, paracrine pro-angiogenic factor secretion and trans-differentiation into endothelial-lineage cells.
  • how: To investigate the vascular regenerative potential of u00adABCB5+ MSCs in_vivo the authors studied . . .

     

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