Translocation of glycogen synthase kinase-3β (gsk-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (vdac2)*

HIGHLIGHTS

  • who: Masaya Tanno from the nerable to exposure to H , have published the research: Translocation of Glycogen Synthase Kinase-3β (GSK-3β), a Trigger of Permeability Transition, Is Kinase Activity-dependent and Mediated by Interaction with Voltage-dependent Anion Channel 2 (VDAC2)*, in the Journal: (JOURNAL) of October/17,/2014
  • what: Among the proteins identified , the authors focused on VDAC2, which was present in spot number 2 in Fig 4B. The authors demonstrated that kinase activity of GSK-3␤ and interaction with VDAC2 are major determinants of GSK-3␤ translocation to mitochondria in response to . . .

     

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