Transmembrane charge separation during the ferryl-oxo ã¢â€ ’ oxidized transition in a nonpumping mutant of cytochrome c oxidase*

HIGHLIGHTS

  • who: Sergey A. Siletsky from the (UNIVERSITY) have published the research: Transmembrane Charge Separation during the Ferryl-oxo → Oxidized Transition in a Nonpumping Mutant of Cytochrome c Oxidase*, in the Journal: (JOURNAL) of September/20,/2004

SUMMARY

    The transfer occurs through the Dchannel, because it is observed also in the N139D/K362M double mutant in which the K-channel is blocked. This was first shown for the N131D mutant of the COX from Paracoccus denitrificans, which places an aspartic acid residue near the entrance of the D-channel. According to the present data . . .

     

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