HIGHLIGHTS
- who: Thomas Langerak and colleagues from the Department of Pediatrics, Division of Neonatology, Erasmus Medical Center, Rotterdam, the Netherlands have published the research: Transplacental Zika virus transmission in ex vivo perfused human placentas, in the Journal: (JOURNAL)
- what: By using this model the authors demonstrate that DENV antibodies significantly increase ZIKV uptake in perfused human placentas and that this increased uptake is neonatal Fc-receptor-dependent. The authors show that cross-reactive DENV antibodies enhance ZIKV infection in term human placental explants and in primary fetal macrophages but not in primary trophoblasts. The authors demonstrate . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.