Transplantation of wnt5a-modified bone marrow mesenchymal stem cells promotes recovery after spinal cord injury via the pi3k/akt pathway

HIGHLIGHTS

  • What: This study explored the potential benefits of bone marrow mesenchymal stem cell (BMSC) transplantation for repairing SCI. This study investigated the role and underlying mechanisms of Wnt5a in promoting neuronal differentiation of BMSCs both in vivo and in vitro.
  • Who: Haimei Yang from the Animals The Ethics Committee for Laboratory Animal Management at Guangzhou University of Chinese Medicine conducted a comprehensive evaluation and approved all animal research activitiesThe experimental protocol for this study is registered in The Second Affiliated Hospital of Guangzhou University of Chinese Medicine. Male Sprague-Dawley (SD) rats weighing, g were . . .

     

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