HIGHLIGHTS
- who: Lingmei Jin from the (UNIVERSITY) have published the Article: Transposable elements activation triggers necroptosis in mouse embryonic stem cells, in the Journal: (JOURNAL) of 20/02/2023
- what: Official journal of CDDpress 2 Here, the authors demonstrate that TEs induce the activation of RIPK3 to trigger necroptosis in SETDB1-KO mESCs under 2iL condition. The authors report that activation of TEs is responsible for necroptosis in the SETDB1 knockout mESC.
- how: These results indicated that H3K9me3marked TE has cis regulatory effect on nearby genes.
SUMMARY
TEs can regulate . . .
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