Transposon silencing in the drosophila female germline is essential for genome stability in progeny embryos

HIGHLIGHTS

  • who: Zeljko Durdevic and collaborators from the Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany have published the research: Transposon silencing in the Drosophila female germline is essential for genome stability in progeny embryos, in the Journal: (JOURNAL)
  • what: The authors show that up-regulated transposons invade the maternal genome, inducing DNA DSBs that, together with transposon RNAs and proteins, are maternally transmitted and consequently cause embryogenesis arrest. The study shows that a transient loss of vas expression during early oogenesis leads to up-regulation of transposon levels and compromised viability of progeny embryos . . .

     

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