Trapping of spermine, kukoamine a, and polyamine toxin blockers in gluk2 kainate receptor channels

HIGHLIGHTS

• What: The authors investigated the trapping of four channel blockers of GluK2 KARs, NpTx-8, PhTx-74, KukoA, and SPM, which demonstrate a broad range of inhibitory potencies (Fig 1).
• Who: Shanti Pal Gangwar from the (UNIVERSITY) have published the Article: Trapping of spermine, Kukoamine A, and polyamine toxin blockers in GluK2 kainate receptor channels, in the Journal: (JOURNAL) of 15/07/2024
• How: The models were tested for overfitting by shifting their coordinates by 0.5 Å (using shake) in Phenix 1.18104 refining each shaken model against a corresponding unfiltered half map . . .
  

   

  

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