Treatment of alcohols with tosyl chloride does not always lead to the formation of tosylates

HIGHLIGHTS

  • who: Rui Ding from the Key Laboratory of Radiopharmaceuticals, College of Chemistry, Beijing Normal University, Beijing have published the article: Treatment of Alcohols with Tosyl Chloride Does Not always Lead to the Formation of Tosylates, in the Journal: Molecules 2011, 16, 5665-5673 of 13/06/2011
  • what: We have shown that it was possible to predict whether chlorination or tosylation would occur for substituted benzyl alcohols and pyridine methanols.
  • how: The authors carried out a series of experiments and tried to discover why chlorination happened instead of tosylation.

SUMMARY

     

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