HIGHLIGHTS
- What: Over the study period minimal invasive surgery was used more often compared to open surgery and was associated with better overall survival. The authors intended to add evidence on risk group dependent effects of different therapeutic approaches. To evaluate the outcome of the surgical approach on overall survival, the analysis focused on patients who underwent open or endoscopic surgery, excluding the low numbers of patients who were subjected to other types of surgical approaches (s. The outcome of the analysis showed that surgery alone reduces overall survival significantly (Cox; HR=1.889; 95% CI=1.561 . . .

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