Treatment of mouse sperm with a non-catalytic mutant of pla2g10 reveals that pla2g10 improves in vitro fertilization through both its enzymatic activity and asligand of pla2r1

HIGHLIGHTS

  • who: Roland Abi Nahed and colleagues from the Institute for Advanced Bioscience, INSERM, CNRS UMR, La Tronche, France have published the Article: Treatment of Mouse Sperm with a Non-Catalytic Mutant of PLA2G10 Reveals That PLA2G10 Improves In Vitro Fertilization through Both Its Enzymatic Activity and asLigand of PLA2R1, in the Journal: (JOURNAL)
  • what: This study shows that the action of PLA2G10 on gametes is complex and can simultaneously activate the catalytic pathway and the PLA2R1-dependent receptor pathway. The presence of sPLA2 binding proteins in gametes and their possible physiological function were never assessed . . .

     

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