Treatment with the ferroptosis inhibitor ferrostatin-1 attenuates noise-induced hearing loss by suppressing ferroptosis and apoptosis

HIGHLIGHTS

  • who: Ferroptosis and colleagues from the Department of Otolaryngology Head and Neck Surgery, Tangdu Hospital, Air Force Medical University, Xi`an, China have published the research work: Treatment with the Ferroptosis Inhibitor Ferrostatin-1 Attenuates Noise-Induced Hearing Loss by Suppressing Ferroptosis and Apoptosis, in the Journal: Oxidative Medicine and Cellular Longevity of 12/07/2022
  • what: The authors explored the protective effect of Fer-1 against NIHL using an in_vivo mouse model and in_vitro oxidative stress models (cochlear explants and HEI-OC1 cells). The authors focused on iron, another key factor in ferroptosis. In . . .

     

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