Treg-driven tumour control by pi3kδ inhibition limits myeloid-derived suppressor cell expansion

HIGHLIGHTS

• who: Sarah N. Lauder from the Received: , October , Revised: , June , Accepted: , July , Published online: , August , Published on Behalf of CR UK have published the Article: Treg-driven tumour control by PI3Ku03b4 inhibition limits myeloid-derived suppressor cell expansion, in the Journal: (JOURNAL)
• what: Using the same 4T1 tumour model, the authors now sought to examine the impact on this MDSC expansion of a pharmacological approach to inhibiting PI3Ku03b4.
• future: As an extension of these studies the authors sought to determine whether pharmacological inhibition of PI3Ku03b4 using the small_molecule inhibitor PI-3065 also targets . . .
  

   

  

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