Trem2 in the pathogenesis of ad: a lipid metabolism regulator and potential metabolic therapeutic target

HIGHLIGHTS

  • who: Rui-Yang Li from the (UNIVERSITY) have published the Article: TREM2 in the pathogenesis of AD: a lipid metabolism regulator and potential metabolic therapeutic target, in the Journal: (JOURNAL)
  • what: The authors propose some potential therapies targeting and discuss the prospect and limitations of these therapies.
  • future: Mechanistic and functional studies are needed to further validate and explore this pathway. It is essential for future studies to explore whether the influence of TREM2 on PIP2 metabolism is associated with or even dependent on ApoE. Although the effect of TREM2 on AD pathogenesis . . .

     

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