Trem2 modulates differential deposition of modified and non-modified aβ species in extracellular plaques and intraneuronal deposits

HIGHLIGHTS

• who: Pranav Joshi from the Tissue samples of patient autopsy cases were provided by the Neurobiobank Munich, Ludwig-Maximilians-University (LMU) MunichDetailed clinical characteristics were ascertained from an integrated autopsy database. Written informed consent for autopsy and analysis of tissue sample data was obtained for all patients, either from the patients themselves or their kin and the samples were collected according to the guidelines of the local ethics committee following all ethical regulations. Information regarding cases, clinical diagnosis, age at death, postmortem delay, fixation time, AD Braak and Braak stage, Thal phase, coding variant is given in . . .
  

   

  

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