Triac treatment improves impaired brain network function and white matter loss in thyroid hormone transporter mct8/oatp1c1 deficient mice

HIGHLIGHTS

  • who: Jonathan Rochus Reinwald and collaborators from the Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany have published the article: TRIAC Treatment Improves Impaired Brain Network Function and White Matter Loss in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice, in the Journal: (JOURNAL)
  • what: The authors characterize impairments of brain structure and function in Mct8/Oatp1c1 DKO using multimodal magnetic resonance imaging (MRI) and assess the potential of the TH analogue 3 30 5-triiodothyroacetic acid (TRIAC) to rescue this phenotype. The study demonstrates prominent structural and functional brain alterations in Mct8/Oatp1c1 DKO that . . .

     

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