Tric controls transcription resumption after uv damage by regulating cockayne syndrome protein a

HIGHLIGHTS

• who: Alex Pines and collaborators from the Leiden University Nijmegen, Geert Grooteplein , GA Nijmegen The Netherlands have published the paper: TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 15/02/2018
• what: The authors provide evidence that disease-associated missense mutations in CSA can lead to enhanced interaction with TRiC and cause cellular mislocalization. The authors demonstrate that one of the components of the PN, the chaperonin TRiC, stably interacts with the core TC-NER protein CSA. Interestingly, this model differs from . . .
  

   

  

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