Tricalbin proteins regulate plasma membrane phospholipid homeostasis

HIGHLIGHTS

• who: Tricalbin proteins regulate plasma and colleagues from the Medical Research Council Laboratory for Molecular Cell Biology, University College London, London, UK Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan have published the research: Tricalbin proteins regulate plasma membrane phospholipid homeostasis, in the Journal: (JOURNAL)
• what: This study is focused on elucidating specific roles of the Tcb proteins in PM homeostasis. The authors propose that the yeast Tcb proteins serve as Ca2+-activated ER-PM tethers and lipid transfer proteins that maintain PS levels necessary for PM integrity under stress conditions (Fig 9).
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