Trifluoromethylcinnamanilide michael acceptors for treatment of resistant bacterial infections

HIGHLIGHTS

  • who: Tomas Strharsky and collaborators from the Department of Chemical Drugs, Faculty of Pharmacy, Masaryk University, Palackeho, Institute of Chemistry, University of Silesia in Katowice, Katowice, Poland have published the Article: Trifluoromethylcinnamanilide Michael Acceptors for Treatment of Resistant Bacterial Infections, in the Journal: (JOURNAL)
  • what: Hibitors, of which the activity was also experimentally evaluated.

SUMMARY

    All the prepared compounds were tested against Gram-positive and mycobacterial strains and were also docked into the binding_site of their potential intracellular target InhA, which has been previously reported to interact with similar compounds. All . . .

     

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