Triggering cell death in cancers using self-illuminating nanocomposites

HIGHLIGHTS

• who: September et al. from the University, China have published the article: Triggering cell death in cancers using self-illuminating nanocomposites, in the Journal: (JOURNAL)
• what: The authors show that the sensitization of TiO2 with luciferase enables ATP activation of TiO2 nanoparticles and mediates an apoptotic cascade within HCT 116 colon cancerous cells. The authors demonstrate that nanocomposites do not show any activity within noncancerous immortalized cells YAMC (young adult mouse colonocytes). The authors explore the strategy for enhancing nanocomposites` retention within the extracellular space, by coupling luciferase-TiO2 nanocomposites (TiDoL) to the C225 antibody . . .
  

   

  

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