Trim33 binds and silences a class of young endogenous retroviruses in the mouse testis; a novel component of the arms race between retrotransposons and the host genome

HIGHLIGHTS

  • who: Luke Isbel and collaborators from the Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Melbourne, Australia have published the paper: Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome, in the Journal: (JOURNAL)
  • what: The authors report a role for Trim33 in silencing a specific subset of retrotransposons that contain RLTR10B LTRs in the germline. The authors report, for the first time, the mutation underlying MommeD44 and the consequences . . .

     

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