Trimeric interactions of the invariant chain and its association with major histocompatibility complex class ii αβ dimers*

HIGHLIGHTS

• who: John R. Newcomb from the (UNIVERSITY) have published the paper: Trimeric Interactions of the Invariant Chain and Its Association with Major Histocompatibility Complex Class II αβ Dimers*, in the Journal: (JOURNAL) of April/29,/1996

SUMMARY

To assess which regions of the I chain are involved in binding class II molecules, the authors have studied proteolytic fragments of the I chain generated both by natural proteolytic degradation of ab dimer-invariant chain complexes (abzI) within human B cells and by in_vitro digestion of purified abzI complexes with proteinase K. The N terminus of . . .

 



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