Trimerization of the n-terminal tail of zika virus ns4a protein: a potential in vitro antiviral screening assay

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  • who: Janet To and Jaume Torres from the School of Biological Sciences, Nanyang Technological University, Nanyang Drive, Singapore , have published the paper: Trimerization of the N-Terminal Tail of Zika Virus NS4A Protein: A Potential In Vitro Antiviral Screening Assay, in the Journal: Membranes 2021, 335 of /2021/
  • what: In both DENV and_(ZIKV) this N-terminal tail (residues 1-48) forms a random coil in solution but becomes mostly α-helical upon interaction with detergents or lipid Herein the authors show that a peptide from ZIKV NS4A that spans residues 4-58 which includes most . . .

     

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