Trophoblast antigens, fetal blood cell antigens, and the paradox of fetomaternal tolerance

HIGHLIGHTS

  • who: Gabrielle Rizzuto and collaborators from the of Pathology, University of California San Francisco, San Francisco, CA have published the Article: Trophoblast antigens, fetal blood cell antigens, and the paradox of fetomaternal tolerance, in the Journal: (JOURNAL) of 28/03/2023
  • what: These ideas have since been largely disqualified for the following reasons. Synthesizing these older observations with more recent work in mice, the authors discuss how the decision between tolerance or immunity to a given fetoplacental antigen appears to be a function of whether the antigen is trophoblast derived-and thus decorated with immunosuppressive . . .

     

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