Trpa1 de�ciency attenuates cardiac �brosis via regulating grk5/nfat signaling in diabetic rats

HIGHLIGHTS

  • who: Posted Date August et al. from the Renmin Hospital of Wuhan University have published the research work: TRPA1 deufffdciency attenuates cardiac ufffdbrosis via regulating GRK5/NFAT signaling in diabetic rats, in the Journal: (JOURNAL)
  • what: TRPA1 was activated in diabetic rat heart tissue and in HG-treated CFs.
  • how: The authors explored the role of CIN in diabetic rats in this study.

SUMMARY

    TRP channels are widely expressed in_vivo and play critical roles in regulating various homeostatic functions. To promote CFs activation in_vitro, cells were exposed to high . . .

     

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