Trpm4 gene invalidation leads to cardiac hypertrophy and electrophysiological alterations

HIGHLIGHTS

• who: Hypertrophy et al. from the France University, United States of America have published the article: Trpm4 Gene Invalidation Leads to Cardiac Hypertrophy and Electrophysiological Alterations, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0115256]. December 22, 2014 of 22/09/2010
• what: The authors aimed to investigate the role of the TRPM4 channel on whole cardiac function with a Trpm4 knock-out mouse (Trpm4-/-) model. The authors showed that deletion of the Trpm4 gene in mice alters the cardiac phenotype with morphological and electrical changes.
• how: For Trpm4 gene_expression comparison . . .
  

   

  

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