Trpm8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine

HIGHLIGHTS

• who: David Alarcu00f3n-Alarcu00f3n from the (UNIVERSITY) have published the paper: TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine, in the Journal: (JOURNAL) of 30/09/2022
• what: The authors propose that the lack of this protective mechanism in females leads to a persistent mechanical hypersensitivity. The authors propose antagonistic roles of TRPA1 and TRPM8 activities determined by the continuous exposure to exogenous and endogenous agonists.
• how: The authors implemented in the laboratory a modification of a previous model of chronic migraine induced . . .
  

   

  

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