HIGHLIGHTS
- who: Christabelle Rajesh et al. from the Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA have published the Article: Truncated O-Glycan-Bearing MUC16 Enhances Pancreatic Cancer Cells Aggressiveness via 41 Integrin Complexes and FAK Signaling, in the Journal: (JOURNAL) of 23/04/2022
- what: This study shows that the CRISPR/Cas9-mediated genetic deletion of in PDAC cells decreases tumor cell migration. Y397 phosphorylation of FAK, as observed in the study , has also been shown to be a downstream effect of integrin signaling . Containing MUC16 . . .
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