HIGHLIGHTS
- who: Vibha Gupta from the Amity University Gurgaon, India have published the paper: Truncation of C-Terminal Intrinsically Disordered Region of Mycobacterial Rv1915 Facilitates Production of ``Difficult-to-Purify`` Recombinant Drug Target, in the Journal: (JOURNAL)
- what: This study reports the difficulties encountered in obtaining soluble expression of the target protein in heterologous host E. coli BL21 (DE3) and mainly focuses on strategies adopted for recovery of active Rv1915/ICL2a.
SUMMARY
Specially, in case of Mtb H37Rv, the two icls that together play an important role in pathogenesis and persistence of . . .
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