Tryptophan challenge in healthy controls and people with schizophrenia: acute effects on plasma levels of kynurenine, kynurenic acid and 5-hydroxyindoleacetic acid

HIGHLIGHTS

  • who: Korrapati V. Sathyasaikumar and collaborators from the Baltimore, MD, USA have published the research work: Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid, in the Journal: Pharmaceuticals 2022, 15, 1003. of 15/08/2022
  • what: Although not the focus of the present study, the mechanisms underlying the maintenance of the substantive increases in circulating kynurenine and KYNA levels over the first few hours after an acute TRP challenge, as well as possible differential effects of these increases on peripheral organs . . .

     

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