Tsg-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress

HIGHLIGHTS

  • who: Xiao Lu from the Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, Nanjing, Jiangsu Province, China have published the Article: TSG-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress, in the Journal: (JOURNAL)
  • what: The authors show, for the first time, that ADSC-sEVs reduce neuronal apoptosis and inhibit BSCB disruption by suppressing ER stress. The studies provide further insight into sEVs-mediated effects on ER stress through PI3K/AKT pathway.

SUMMARY

     

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