HIGHLIGHTS
- who: TYPE and collaborators from the University of California, Riverside, United States have published the research: Tuberactinomycin antibiotics: Biosynthesis, anti-mycobacterial action, and mechanisms of resistance, in the Journal: (JOURNAL)
- future: The influence of ribose methylation on C1920 sugar pucker and H69 helical structure influencing the architecture of the common binding at the tip of H69 site has recently been proposed (Laughlin et_al 2022) but further studies are needed to tease apart these important molecular details of tuberactinomycin action on the ribosome.
SUMMARY
Use of these drugs as second-line treatments . . .
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