HIGHLIGHTS
- who: Guoqing Wang from the University of Brescia, Italy have published the research: Tumor-associated microglia and macrophages in glioblastoma: From basic insights to therapeutic opportunities, in the Journal: (JOURNAL)
- what: In this review, the authors focus on the protumor effects of TAMs in GBM .
- how: The results indicated that the expression of surface major histocompatibility complex class II (MHC class II) and costimulatory molecules CD40 CD80 and CD86 were reduced in TAMs thus inhibiting antigen cross-presentation and T_cells activation .
SUMMARY
GBM is characterized by a lack of . . .
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