Tumor-derived exosomal protein tyrosine phosphatase receptor type o polarizes macrophage to suppress breast tumor cell invasion and migration

HIGHLIGHTS

  • who: Hao Zhang from the Institute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou, China have published the research work: Tumor-Derived Exosomal Protein Tyrosine Phosphatase Receptor Type O Polarizes Macrophage to Suppress Breast Tumor Cell Invasion and Migration, in the Journal: (JOURNAL)
  • what: The authors showed that PTPRO plays a role in immune infiltration in breast cancer. The studies showed that tumor cell-derived exosomal PTPRO inhibits invasion and migration abilities of breast cancer cells via modulating TAM polarization.
  • how: Three independent experiments were carried out in triplicate . . .

     

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