HIGHLIGHTS
- who: Jian Gao from the , have published the research work: Tumor endothelial cell-derived extracellular vesicles contribute to tumor microenvironment remodeling, in the Journal: (JOURNAL)
- what: In this review the authors describe the current knowledge on EVs derived from ECs and the authors examine how these EVs affect TME remodeling.
SUMMARY
A gastric cancer study reported that the EV cargoes inhibin subunit βA and thrombospondin 2 were secreted by CAF-derived EVs to the TME to promote cancer. Among the multiple stromal cell types in the TME, endothelial cells (ECs) are . . .
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