Tumor fractions deciphered from circulating cell-free dna methylation for cancer early diagnosis

HIGHLIGHTS

  • who: Xiao Zhou from the (UNIVERSITY) have published the research: Tumor fractions deciphered from circulating cell-free DNA methylation for cancer early diagnosis, in the Journal: (JOURNAL) of 28/Nov/2022
  • what: The authors show that the estimated fractions of tumor-derived cfDNA from cancer patients increase significantly as cancer progresses in two independent datasets. The authors provide an effective tool that can be applied to monitor tumor progression and has a great potential for large-scale cancer screening. Instead of manually constructing a reference atlas, the authors propose to learn a reference database from . . .

     

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