HIGHLIGHTS
- who: Top from the Department of Biological Sciences, University Esplanade, Kent State University, Kent, Ohio, USA have published the Article: tumor growth in vivo, in the Journal: (JOURNAL)
- what: The authors show that the small molecule antagonist MK-2206 when combined with the Th1 cytokines IFN-gamma and TNF-alpha maximize indicators of apoptotic cell death in a panel of phenotypicallydiverse human breast cancer lines. Given the heavy investment in developing small_molecule inhibitor drugs, both in dollars and in man-hours of research, it is reasonable to explore all avenues to obtain their maximal therapeutic . . .
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