Tumor heterogeneity in vhl drives metastasis in clear cell renal cell carcinoma

HIGHLIGHTS

• who: Junhui Hu from the (UNIVERSITY) have published the research: Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma, in the Journal: (JOURNAL) of 13/01/2023
• what: This study seeks to understand the metastatic crosstalk at play between the VHL+ and VHL- tumor cells in ccRCC. The rate of PDX engraftment in CAM is 80%.32 Here, the authors focused on the most aggressive metastatic ccRCC, case #22 . Amongst these four genes, the authors focused on POSTN because it encodes a secreted celladhesion protein upregulated in EMT that correlates with aggressive . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.