Tumor hypoxia regulates immune escape/invasion: influence on angiogenesis and potential impact of hypoxic biomarkers on cancer therapies

HIGHLIGHTS

  • who: Raefa Abou Khouzam from the University of Lausanne, Switzerland have published the research: Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies, in the Journal: (JOURNAL)
  • what: The authors discuss how combinational approaches considering the hypoxic state of the tumor as well as immune infiltration could prove impactful as surrogate biomarkers for the success of vascular normalization.

SUMMARY

    Hypoxia, as an integral component of the tumor microenvironment and especially of the pathologically vascularized zones inside solid tumors contributes to immune tolerance . . .

     

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