Tumor lactic acidosis: protecting tumor by inhibiting cytotoxic activity through motility arrest and bioenergetic silencing

HIGHLIGHTS

  • who: Angelika J. Fischbeck from the Immunoanalytics, Helmholtz Center Munich, Munich, Germany, Medizinische Klinik und Poliklinik IV, Ludwig-MaximiliansUniversity Munich, Munich, Germany, Department of Biology II, Ludwig-Maximilians-University Munich, Martinsried have published the research: Tumor Lactic Acidosis: Protecting Tumor by Inhibiting Cytotoxic Activity Through Motility Arrest and Bioenergetic Silencing, in the Journal: (JOURNAL)

SUMMARY

    Immunotherapies, foremost immune checkpoint blockade (ICB) and adoptive T_cell therapy (ACT), have changed the landscape of cancer treatment by producing long-lasting and durable responses in a number of patients, even in those where all available treatment options . . .

     

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