HIGHLIGHTS
- who: Palanisamy Nallasamy from the (UNIVERSITY) have published the research: Tumor microenvironment enriches the stemness features: the architectural event of therapy resistance and metastasis, in the Journal: (JOURNAL)
- how: This review discusses the present knowledge on the TME its involvement in CSC maintenance and how these processes translate into metastasis and therapeutic resistance in cancer.
SUMMARY
Stroma forms a favorable milieu around the tumor cells, which is denoted as the "tumor microenvironment (TME)". The authors described how non-genetic determinants and a cascade of events promoting stem_cell enrichment might initiate metastasis . . .
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