Tumor necrosis factor-alpha disrupts cx43-mediated corneal endothelial gap junction intercellular communication

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  • who: Jufeng Meng et al. from the School of Life Science and Technology, ShanghaiTech University, Shanghai, China have published the article: Tumor Necrosis Factor-Alpha Disrupts Cx43-Mediated Corneal Endothelial Gap Junction Intercellular Communication, in the Journal: Oxidative Medicine and Cellular Longevity of 19/09/2022
  • what: The authors determined the effect of TNF-u03b1 on gap junction intercellular communication (GJIC) in rabbit corneal endothelium. The authors demonstrated that TNF-u03b1 inhibits rabbit corneal endothelial GJIC by decreasing the interaction between ZO1 and Cx43, downregulating the expression of Cx43 and disrupting the distribution of Cx43 . . .

     

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