Tumor resident memory cd8 t cells and concomitant tumor immunity develop independently of cd4 help

HIGHLIGHTS

  • who: Terry R. Medler from the Institut State University have published the paper: Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help, in the Journal: Scientific Reports Scientific Reports
  • how: To evaluate whether antigen-specific responses to the expressed model antigen can be generated in tumorbearing mice the authors evaluated the response to a strong vaccine also bearing the model antigen. Given that prior data indicates that Nur77 induction correlates with TCR au00ad ffinity29 this data is consistent with studies showing that Trm have higher antigen u00adaffinity830. Data were . . .

     

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