Tumor-stroma ratio and programmed cell death ligand 1 expression in preoperative biopsy and matched laryngeal carcinoma surgical specimen

HIGHLIGHTS

SUMMARY

To quantify this component, recent studies have identified several measurable parameters on histological sections, including tumor to stroma ratio (TSR). Other parameters that are probably linked to tumor-stroma interaction, such as the type of stroma (fibrotic or desmoplastic), tumor growth pattern, neoplastic nest size and the presence of tumor budding, preliminarily showed a prognostic role in head and neck carcinoma. Pathological Variables Table 1 shows the concordance between biopsies and paired surgical specimens in terms of characterization of TSR, stroma type, large cell nests and tumor budding. Variables on Surgical Specimens TSR on . . .

 



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