HIGHLIGHTS
- who: Koen Brummel from the (UNIVERSITY) have published the Article: Tumour-infiltrating lymphocytes: from prognosis to treatment selection, in the Journal: (JOURNAL) of 23/Dec/2022
- what: Even though upregulation of PD-1 has a detrimental effect on classic CD8+ T_cell functions such as cytotoxic activity and cytokine production and secretion, the study shows that TILs with high expression of PD-1 also acquire novel effector functions.
SUMMARY
Diverse search terms were used, including, but not limited to "tumour-infiltrating lymphocytes", "TILs", "T_cells", "T lymphocytes", "CD3 T_cells, "CD8 T_cells", "CD4 T_cells . . .
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