Tuning of the na,k-atpase by the beta subunit

HIGHLIGHTS

  • who: Florian Hilbers from the Danish Research InstituteAarhus University , Aarhus, Denmark have published the research work: Tuning of the Na,K-ATPase by the beta subunit, in the Journal: Scientific Reports Scientific Reports
  • what: Guided by the electrophysiological measurements, the authors focused the analyses on the transmembrane region of the β subunits and their interactions with α. The authors show that, compared to β 1 and β 3, β 2 markedly shifts the E1P-E2P equilibrium towards the E1P state (right-shift of the Q/V curve) (Fig 1 and Supplementary Fig S2) and increases the rate constants at hyperpolarized . . .

     

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