HIGHLIGHTS
- who: Tuning strand displacement kinetics et al. from the Northwestern University, Evanston, IL, USA have published the Article: Tuning strand displacement kinetics enables programmable ZTP riboswitch dynamic range in vivo, in the Journal: (JOURNAL) of October/20,/2022
- what: Using functional mutagenesis with Escherichia coli gene expression assays the authors show that mutations designed to slow of the expression platform enable precise of riboswitch dynamic range (2.4-34-fold) depending on the type of kinetic barrier introduced and the position of the barrier relative to the nucleation site.
SUMMARY
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