HIGHLIGHTS
SUMMARY
Demonstrate that temperature increase triggers a cascade of local amino_acid-to-amino_acid dynamics that remarkably resembles the allosteric activation that takes place upon effector binding. The EC entries are scores indicating how central each residue is to the intercommunication established by nuclear motions, pinpointing key amino_acids that participate in the IGPS dynamics44. To understand how the crosstalk between the effector binding_site and the active_site of IGPS is modified by temperature, the authors studied the optimal residue-to-residue communication_channels connecting the PRFAR phosphate binding_sites with the catalytic_site in HisH. The apo30 has mostly 2 . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.