Tut4/7-mediated uridylation of a coronavirus subgenomic rnas delays viral replication

HIGHLIGHTS

  • who: Ankit Gupta from the National Institute have published the paper: TUT4/7-mediated uridylation of a coronavirus subgenomic RNAs delays viral replication, in the Journal: (JOURNAL)
  • what: The authors investigate the role of TENTs in the replication of the mouse hepatitis virus (MHV) a member of the Betacoronavirus genus. The authors propose that TUT4/7 directly target sgRNAs to promote their decay which in turn limits the replication capacity of the virus.

SUMMARY

    Received: 2 June 2022; Accepted: 5 April 2023. @@

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